Ghent University

Post-Doc, Medicine and Health Sciences

PhD

Thesis Title: The effect of cigarette smoke on mucosal immunity in the small intestine

Claude Cuvelier

About

Study of the immune system in the gut, more in particular the Peyer's patches and the epithelium covering Peyer's patches, the follicle-associated epithelium (FAE).
FAE is the site where the first lesions in Crohn's disease (CD), a chronic inflammatory disease of the bowel, are found. Smokers have a higher risk for developing CD, but the role of cigarette smoke in the pathogenesis of CD is poorly understood. A better understanding of the influence of smoke on the immune system of the gut will help us to understand why smokers are more vulnerable to develop CD.

 

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